
In this blog, we took an in-depth look at Hydroxypropyl Methylcellulose (HPMC), a plant-based compound that revolutionized the nutritional supplement and pharmaceutical industries. We found that HPMC not only provides functional benefits as a thickener and stabilizer, but is also a safe and inclusive alternative to gelatin, making it suitable for a wide audience, including vegetarians and vegans.
The approval from regulatory authorities such as EFSA and the FDA emphasizes the safety of HPMC, supported by extensive scientific studies. Furthermore, the moisture-resistant properties and thermal stability of HPMC in capsule and tablet forms are undeniable, contributing to the quality and sustainability of nutritional supplements.
I have also found a number of forums online where people have made the connection between bloating, wind and discomfort, to eating foods (or supplements) that contain it.

20. The relationship between HPMC viscosity and temperature should be taken into account in practical applications?
The present assessment is based on data submitted by the applicant in the form of a technical dossier5 in support of the authorisation request for the use of HPMC as a feed additive.

Low-viscosity hydroxypropyl methylcellulose is mainly used for self-leveling mortar. Its viscosity is low, although its water retention is poor. HPMC 's leveling property is good, and the mortar is dense. Medium and low-viscosity HPMC is mainly used in tile adhesives, joint fillers, anti-cracking mortars, and thermal insulation mortars. It has good constructability, a good water retention effect, and high mortar density. HPMC exists as a water-retaining agent in mortar. Its water-retaining properties prevent the paste from drying too quickly. And cracking after reapplying.


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Chemical composition and origin
Hydroxypropyl methylcellulose (HPMC) is produced by treating natural cellulose with methyl chloride and propylene oxide. Cellulose, the basis of HPMC, is an organic compound found in the cell walls of plants, giving HPMC its plant origin. During the production process, hydroxypropyl and methyl groups are added to the cellulose chain. This chemical process improves the solubility of HPMC in cold water and increases its gelation temperature, making it particularly useful in applications requiring thermal stability.
Comparison with other thickeners
Compared to other thickeners such as gelatin, which is of animal origin, HPMC offers a crucial advantage: it is 100% vegetable. This not only makes HPMC suitable for vegetarians and vegans, but also offers significant advantages in terms of stability and shelf life. HPMC is less susceptible to microbial degradation than gelatin, which is especially important for nutritional supplements and medications that require storage in various climates and conditions. In addition, HPMC is resistant to pH fluctuations. While gelatin can break down or lose its effectiveness at different pH levels, HPMC maintains its stability over a wide pH range, making it an excellent choice for formulations that require consistent performance regardless of the acidic or basic conditions in which they are used .